Article Update

Wednesday, August 19, 2020


Dupuytren contracture is a progressive thickening and contracture of the palmar aponeurosis (fascia) that results in flexion deformities of the finger joints. Although its cause is unknown, trauma is not a factor in its origin (but can accelerate progression) and an increased familial incidence suggests a genetic component. Dupuytren contracture chiefly affects middle-aged white men, particularly those of northern European descent. It most commonly affects the ring and small fingers, followed infrequently by long finger involvement. It rarely affects the index finger or the thumb.


The first sign of the condition is a slowly enlarging, firm, and slightly painful nodule that appears under the skin near the distal palmar crease opposite the ring finger; other nodules may form at the bases of the ring and small fingers. Subcutaneous contracting cords develop later; they extend proximally from the nodule toward the base of the palm and distally into the proximal segment of a finger.
Flexion contractures gradually develop in the meta-carpophalangeal joint and later in the proximal inter- phalangeal joint of the involved finger. The degree of the flexion deformities and their development rate vary, depending on the extent of thickening and contracture in the palmar fascia. Some contractures develop quickly over a few weeks or months; others take several years. Long remissions may occur, only to be followed by exacerbations and increasing deformity. As the flexion deformity progresses, secondary contractures occur in the skin, nerves, blood vessels, and joint capsules. Because there is no tendon involvement, active flexion of the fingers remains complete. Involvement is usually bilateral; and in 5% of patients, similar contractures occur in the feet.
Serious changes occur in the skin overlying the involved fascia. The short fascial fibers that extend from the palmar aponeurosis to the skin contract and draw folds of skin inward, producing dimpling, pitting, fissuring, and puckering. The subcutaneous fat atrophies, and the skin becomes thickened, less mobile, and attached firmly to the underlying involved fascia. These changes occur particularly in the region of the distal palmar crease on the ulnar side of the palm. Except for the nodules, cords, and finger contractures, the patient has few complaints. Developing nodules may be slightly painful and tender. Finger deformities interfere with use of the hand, leading to disability in patients with certain occupations. The stages are not distinct and description of them is not essential.

Surgery is the only effective treatment and should be done before the skin has deteriorated and the skin, nerves, and joint capsules have become too contracted. A typical timing for surgery is when the patient can no longer lay the hand flat on the table and definitely when contracture occurs at the proximal interphalangeal joint. Surgical repair should not be performed before contractures develop.
Partial fasciectomy, the most common treatment, removes all of the thickened and contracted aponeurosis without excision of the uninvolved portion. During fasciectomy, tourniquet hemostasis is essential because hematoma is the most common complication. Skin flaps must be reflected very carefully to avoid buttonholing of the skin and necrosis and the subsequent need for skin grafts. However, an open palm technique has been successfully utilized by making a distal palmar trans- verse crease; and after full extension is obtained, the wound edges gap open often more than 2 cm. This can be treated with dressing changes, and it typically heals over time by wound contracture and epithelialization. In addition, great care must be taken to avoid any damage to the nerves and blood vessels that may be surrounded and distorted by the hypertrophic fibrous tissue. Neurovascular bundles are at times drawn across the midline of the finger, making them difficult to identify and easy to injure. Resection of Dupuytren contractures requires a keen knowledge of anatomy and surgical exposures to avoid neurovascular injury.

After surgery, the fingers are not initially splinted as was done in the past because this avoids overstretching the neurovascular bundles, which can lead to neurapraxia, followed by a dystrophic response and complex regional pain syndrome. After 5 to 7 days, splinting is initiated and splints are adjusted weekly to bring the fingers gradually into the corrected extended position. Prolonged postoperative care, which may require several months, is necessary to obtain optimal results and includes splinting the hand in the flat position between exercise sessions.
Percutaneous fasciotomy is reserved for poor-risk, elderly persons or as a preliminary procedure to fasciectomy in patients who have marked contractures; tight, adherent skin; and shortening of nerves and joint capsules. The results are better when this procedure is done in the residual stage of the contracture rather than during active progression of the disease.

Share with your friends

Give us your opinion
This is just an example, you can fill it later with your own note.