FEMALE URETHRA - pediagenosis
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Monday, September 20, 2021




The urethra, situated at the lowest portion of the bladder and passing downward and forward beneath the symphysis, varies from 3 to 5 cm in length and averages about 6 mm in diameter. The angle formed by the internal urethral orifice and the bladder at the bladder neck and surrounded by the intrinsic sphincter is critical to maintaining normal urinary continence; to with-stand the hydrostatic pressure of the bladder, this area is further supported by the fascia and tensing muscles of the pelvic diaphragm. Its mucosal surface is thrown into longitudinal folds by the constricting action of the external supporting structures. The most prominent of these longitudinal folds, situated on the posterior aspect of the urethra, is sometimes referred to as the urethral crest. The endopelvic fascia that covers the bladder is continuous over the entire urethra just below the mucosal layer, and contiguous to it is a thin layer of erectile tissue formed by the cavernous venous plexus. The muscular coats that surround the bladder also cover the urethra but become thinner as it passes down-ward toward the external meatus. The upper two-thirds of the urethra lie behind the symphysis pubis and are referred to as the intrapelvic urethra. It is this portion that passes through the musculofascial attachments forming the interlevator cleft. The perineal portion extends from the superior fascia of the urogenital diaphragm to the meatus. As it passes through the urogenital diaphragm, the urethra is surrounded by the sphincter urethrae membranaceae, the homologue of the muscle of the same name in the male but a far weaker and less important structure. Near the external meatus, the urethra is adjacent to the upper ends of the vestibular bulbs and the surrounding bulbocavernosus muscles. At its meatus, the urethra lies in the anterior vaginal wall between the folds of the labia minora 2 to 3 cm below the clitoris. Along its entire length, but especially in its perineal portion, the urethra is perforated by the openings of numerous small periurethral glands, the homologues of the prostatic ducts in the male.

The schematic reconstruction of this duct system shows that although the ducts of the small glands may enter the urethra independently, the majority of them form an interdependent conducting system terminating in the large paraurethral (Skene) ducts, which open on either side of the midline, posterior to the urethral meatus. These are vestigial remnants that serve no specific purpose but are important in that their position predisposes them to infection, especially by the gonococcus, and that their relatively poor drainage increases the risk of a chronic infection.

Cross sections through the lower urethra show the mucosal folds and the immediate supporting structures:

The submucosal lamina propria is a loose network of fibrous and elastic tissue containing a prominent venous system, the cavernous plexus or corpus spongiosum, which accounts for the extreme vascularity in the area. The muscle coats consist of an inner longitudinal and an outer circular layer, both quite thin and mutually interdependent. A thin layer of striated muscle referred to as the external sphincter and supplied by the pudendal nerve also surrounds the lower urethra, but these distal muscle groups have little to do with micturition. Under high-power microscopy, it can be seen that the epithelium of both the urethra and the periurethral ducts are of the stratified squamous type. The epithelium of the intrapelvic portion of the urethra, as it approaches the bladder neck, tends to be transitional. The glandular epithelium, on the other hand, is of the columnar type, not infrequently stratified. The submucosal connective tissue is relatively poor in cells.

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