STEM CELL THERAPY
Recent approaches to stem cell therapy after a spinal cord injury are depicted here. I. The pathologic process of spinal cord injury shows acute and chronic responses.
II. Use of exogenous stem cells transplanted during the subacute phase leads to differentiation of neurons and glia and trophic support and modulation of inflammation. III. In situ modulation of endogenous stem cells uses infusion of growth factors. These approaches remain experimental but offer possible applications of knowledge derived from stem cell biology to treat devastating conditions such as spinal cord injury.